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10.1371/journal.pone.0120270 491 YadavS

Daily doses up to 500mg of oral glutathione are safe for up to 2 months

It may have nothing to do with the B12 itself

While specific nutrients like B vitamins and NAD+ do play a scientifically established role in cellular energy metabolism , the perceived "energy boost" in otherwise healthy, non-deficient individuals might largely be a consequence of correcting subclinical dehydration or a powerful placebo effect, rather than a direct pharmacological action of the infused vitamins

Pantothenic Acid (Vitamin B5), Coenzyme A and Related Compounds

Pregnancy and Nursing : Always seek advice from a healthcare professional if you are pregnant or breastfeeding before starting glutathione supplementation